منابع مشابه
Surprise Search for Evolutionary Divergence
Inspired by the notion of surprise for unconventional discovery we introduce a general search algorithm we name surprise search as a new method of evolutionary divergent search. Surprise search is grounded in the divergent search paradigm and is fabricated within the principles of evolutionary search. The algorithm mimics the self-surprise cognitive process and equips evolutionary search with t...
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Recent large-scale studies of evolutionary changes in gene expression among mammalian species have led to the proposal that gene expression divergence may be neutral with respect to organismic fitness. Here, we employ a comparative analysis of mammalian gene sequence divergence and gene expression divergence to test the hypothesis that the evolution of gene expression is predominantly neutral. ...
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The structurally constrained protein evolution (SCPE) model simulates protein divergence considering protein structure explicitly. The model is based on the observation that protein structure is more conserved during evolution than the sequences encoding for that structure. In the previous work, the SCPE model considered only the tertiary structure. Here we show that the performance of the mode...
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ژورنال
عنوان ژورنال: Nature
سال: 1960
ISSN: 0028-0836,1476-4687
DOI: 10.1038/187446a0